A world first in depicting the full glycolytic pathway using detailed 3D animation.
This mode-of-action animation explains a rare hemolytic disease, called Pyruvate Kinase Deficiency or PK deficiency — created and produced for a biotech team that develops novel therapeutics for rare diseases and cancers via metabolic intervention.
3D Animations (US + Global Markets)
Our objectives are to visualize the pathophysiology, the current state of supportive care and addressing the unmet need in understanding the root cause of the disease, as well as highlighting the possible treatment for PK deficiency.
Pyruvate kinase deficiency is an inherited lack of the enzyme pyruvate kinase (PK), which is used by red blood cells. Without this enzyme, red blood cells break down too easily, resulting in a low level of these cells (hemolytic anemia).
PK deficiency is passed down as an autosomal recessive trait. This means that a child must receive the non-working gene from both parents to develop the disorder.
Pyruvate kinase deficiency is found in people of all ethnic backgrounds. However, certain populations, such as the Amish, are somewhat more likely to develop the condition.
References: nih.gov, scripps.org
Senior Product Manager, Rare Genetic Disease, Agios Pharma, Massachusetts, USA
A medical technology animation, revolutionizing therapeutic blood purification.
+44 (0) 20 7183 9412 - UK
+1 646 568 4358 - USA
Claremont House, Suite 6,
22-24, Claremont Road,
KT6 4QU, UK