Mechanism-of-action animation exploring the role of PARP inhibitors in breast cancer.
In this animation, we were tasked with explaining the role of Poly(ADP-ribose) polymerase (PARP) inhibitors as a treatment for breast cancer patients with BRCA1 and BRCA2 mutations. We explain how PARP is a protein involved in repairing single-stand breaks in DNA, and inhibition of this enzyme prevents DNA repair, resulting in the accumulation of single-strand breaks.
Deliverables
Oncology Event Animation
Educational Material
Client
Oncology Meeting
PARP helps repair DNA when it becomes damaged. DNA damage may be caused by many things, including exposure to UV light, radiation, certain anticancer drugs, or other substances in the environment.
In cancer treatment, blocking PARP may help keep cancer cells from repairing their damaged DNA, causing them to die. PARP inhibitors are a type of targeted therapy. Also called poly (ADP-ribose) polymerase inhibitor.
Reference: NIH - National Cancer Institute
Obstructive Sleep Apnea
An animation for a prescription-only device which uses electrical muscle stimulation to treat obstructive sleep apnea.
Suite 6, Claremont House,
22-24, Claremont Rd.,
Surbiton, Surrey,
KT6 4QU, UK
